Conclusions: Overall, there was no evidence for alveolar macrophage polarization in sarcoidosis. However, there was a reduced TLR2 mRNA expression in patients with Lofgren’s syndrome, which may be of relevance for macrophage interactions with a postulated sarcoidosis pathogen, and for the characteristics of the ensuing T cell response. (Source: Respiratory Research) MedWorm Message: Register for [...]

No evidence of altered alveolar macrophage polarization, but reduced …7thSpace Interactive (press release)Sarcoidosis is a granulomatous inflammatory disease, possibly of infectious aetiology. We aimed to investigate whether the degree of functional polarization … Source: sarcoidosis – Google News